Carafate: Uses, Dosage, Side Effects

While Lithobid (lithium) has the potential to interact with many drugs including SSRIs, NSAIDs, ACE inhibitors, just to name a few, it does not appear to interact with Synthroid. Taking levothyroxine and sucralfate too close together may interfere with the absorption of levothyroxine and reduce its effectiveness. To prevent or minimize potential interaction, these medications should preferably be taken at least four hours apart. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug Interactions between Carafate and levothyroxine

• The prescribing information for each drug, as published on DailyMED, is also used.
• It is best to take other drugs 2 hours before or after sucralfate to avoid drug interactions.
• Tell your doctor about all your current medicines and any medicine you start or stop using.
• Synthroid should be administered on an empty stomach at the same time each day, at least 30 to 60 minutes prior to a meal.
• Additionally, she takes some over-the-counter products including Alli and Caltrate.

If you are unsure whether one of your medicines interacts with levothyroxine, talk to your doctor or pharmacist. Make sure to always give all of your healthcare providers a full list of your medications (prescription and nonprescription) and any supplements you take. This will help you and your doctors to evaluate all possible interactions and come up with a plan to avoid or minimize them.

Carafate (sucralfate) is an anti-ulcer medication used to treat duodenal ulcers. While this interaction is unlikely to cause significant problems, it could intensify side effects or reduce the effectiveness of one or both synthroid truth medications. Monitoring for changes in symptoms and your condition is recommended, and adjustments may be made if needed to manage any increased or more pronounced side effects. Usually it should be taken at least 30 to 60 minutes before eating breakfast, or at bedtime (3 or more hours after the evening meal).

Consequently, TSH levels should be monitored approximately 6 to 8 weeks after initiating treatment and dose changes. In general, it is not necessary to discontinuethe drug that is reducing levothyroxineabsorption (see box above right). The interactionsgenerally can be circumvented byappropriate adjustment of the dosingtimes of the levothyroxine relative tothe binding agents. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. A reproduction study in rats at doses up to 38 times the human dose did not reveal any indication of fertility impairment.

Dosing information

• If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.
• Concomitant use of levothyroxine and sucralfate may decrease levothyroxine efficacy by binding to and delaying or preventing levothyroxine absorption, potentially resulting in hypothyroidism.
• Equivalence of sucralfate oral suspension to sucralfate tablets has not been demonstrated.
• Variability inendogenous thyroid function probablyaccounts for the large variation in theoutcome of these interactions.
• Concomitant use of levothyroxine and sucralfate may result in reduced levothyroxine efficacy, which may result in hypothyroidism.

Drug interactions of Carafate may include reactions with other drugs taken at the same time, preventing their full absorption. It is best to take other drugs 2 hours before or after sucralfate to avoid drug interactions. Tell your doctor if you are taking cimetidine, digoxin, levothyroxine, phenytoin, quinidine, ranitidine, tetracycline, theophylline, blood thinners, certain antibiotics, and all medications and supplements you use.

Does Carafate interact with my other drugs?

These foods should be avoided within several hours of dosing if possible. Synthroid (levothyroxine) is the most prescribed drug for the treatment of hypothyroidism. While Synthroid is generally considered to be the drug of choice for patients with hypothyroidism, it has specific instructions for administration to ensure proper absorption. Synthroid should be administered on an empty stomach at the same time each day, at least 30 to 60 minutes prior to a meal. Absorption of the drug may be decreased if administered with foods such as soybean flour, cottonseed meal, walnuts, dietary fibers, and grapefruit juice.

The majority of patients had underlying medical conditions that may predispose to bezoar formation (such as delayed gastric emptying) or were receiving concomitant enteral tube feedings. It’s important to note that all medical situations are unique, and management approaches should be tailored to individual circumstances. Patients should always consult their healthcare provider for personalized advice and guidance on managing drug interactions effectively.

Individual drug-drug interaction detail pages contain references specific to that interaction. You can click on the reference number within brackets ” to see what reference was utilized. The theorized or clinically determined reason (i.e., mechanism) why the drug-drug interaction occurs. You may be able to take other medications with levothyroxine, but some of them will have to be taken at a different time from when you take your levothyroxine. To view an interaction report containing 4 (or more) medications, please sign in or create an account.

Brand Names Associated with Sucralfate

The patient is also taking Caltrate which contains calcium carbonate. Phosphate binders (e.g., calcium carbonate, ferrous sulfate, sevelamer) may bind to Synthroid and decrease the serum concentration. As a result, Synthroid and Caltrate should be administered at least 4 hours apart.

Levothyroxine with Sucralfate Interaction Details

Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Equivalence of sucralfate oral suspension to sucralfate tablets has not been demonstrated. Lower than usual dosages are recommended for elderly patients and adolescents. This interaction could result in very serious and potentially life-threatening consequences. If you are taking this drug combination, it is very important to be under close medical supervision to minimize severe side effects and ensure your safety.